Serum Urate Level. Impaired renal function pregnancy-induced hypertension diuretics fasting hyperlactataemia hyperketonaemia and low dose salicylates can all produce increased urate levels. Elevated SU levels are often found in patients with CKD but it is not clear whether high serum urate is a cause of kidney disease or just a common co-occurrence.
Serum concentrations of uric acid the end product of the metabolism of purine compounds above 7 mgdL result in hyperuricemia causally associated with gout as evidenced in randomized clinical trials using urate lowering therapies All or nearly all urate is filtrated out at the glomerulus and decreased efficiency of renal uric acid excretion is responsible for about. High serum urea level is the indication of some serious condition in the body. Epidemiological studies have shown strong correlations between serum urate SU levels and chronic kidney disease CKD risk.
Elevated serum urate levels cause gout and correlate with cardiometabolic diseases via poorly understood mechanisms.
Serum urate levels should be checked to confirm hyperuricaemia and to monitor response to treatment. SUA is a feasible measure of hyperuricemia in gout. 40-85 mgdL or 024-051 mmolL Adult female. Increased urea production obstruction of urinary outflow and acute renal failure can also be the cause.